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Giuseppe Meroni Selected Research

Leukemia

1/2020Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition.
1/2017Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
2/2016Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.

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Giuseppe Meroni Research Topics

Disease

5Neoplasms (Cancer)
12/2023 - 10/2014
3Leukemia
01/2020 - 02/2016
2Virus Diseases (Viral Diseases)
12/2023 - 10/2014
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 01/2017
1COVID-19
12/2023
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017
1Neuroblastoma
01/2017

Drug/Important Bio-Agent (IBA)

3Lysine (L-Lysine)FDA Link
12/2023 - 03/2015
2Histone DemethylasesIBA
01/2017 - 10/2014
1SteroidsIBA
12/2023
1Antiviral Agents (Antivirals)IBA
12/2023
1Mechanistic Target of Rapamycin Complex 1IBA
01/2020
1AminesIBA
01/2017
1Oxidoreductases (Dehydrogenase)IBA
01/2017
1Flavin-Adenine Dinucleotide (FAD)IBA
01/2017
1Monoamine Oxidase (MAO)IBA
02/2016
1Histones (Histone)IBA
03/2015

Therapy/Procedure

2Oral Administration
01/2017 - 02/2016
1Therapeutics
01/2017